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Gene Expression Profiling --- Databases, Nucleic Acid --- Hyperlipidemias --- Apolipoproteins E --- statistics & numerical data --- statistics & numerical data --- genetics --- genetics

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Praise for the third edition of Bioinformatics “This book is a gem to read and use in practice.” —Briefings in Bioinformatics'This volume has a distinctive, special value as it offers an unrivalled level of details and unique expert insights from the leading computational biologists, including the very creators of popular bioinformatics tools.'—ChemBioChem “A valuable survey of this fascinating field... I found it to be the most useful book on bioinformatics that I have seen and recommend it very highly.” —American Society for Microbiology News “This should be on the bookshelf of every molecular biologist.” —The Quarterly Review of Biology The field of bioinformatics is advancing at a remarkable rate. With the development of new analytical techniques that make use of the latest advances in machine learning and data science, today's biologists are gaining fantastic new insights into the natural world's most complex systems. These rapidly progressing innovations can, however, be difficult to keep pace with. The expanded fourth edition of the best-selling Bioinformatics aims to remedy this by providing students and professionals alike with a comprehensive survey of the current field. Revised to reflect recent advances in computational biology, it offers practical instruction on the gathering, analysis, and interpretation of data, as well as explanations of the most powerful algorithms presently used for biological discovery. Bioinformatics, Fourth Edition offers the most readable, up-to-date, and thorough introduction to the field for biologists at all levels, covering both key concepts that have stood the test of time and the new and important developments driving this fast-moving discipline forwards. This new edition features: New chapters on metabolomics, population genetics, metagenomics and microbial community analysis, and translational bioinformatics A thorough treatment of statistical methods as applied to biological data Special topic boxes and appendices highlighting experimental strategies and advanced concepts Annotated reference lists, comprehensive lists of relevant web resources, and an extensive glossary of commonly used terms in bioinformatics, genomics, and proteomics Bioinformatics is an indispensable companion for researchers, instructors, and students of all levels in molecular biology and computational biology, as well as investigators involved in genomics, clinical research, proteomics, and related fields.

Computational Biology --- Sequence Analysis --- Base Sequence --- Databases, Nucleic Acid --- Databases, Protein --- methods --- Base Sequence. --- Databases, Nucleic Acid. --- Databases, Protein. --- Methods. --- methods. --- Bioinformatics --- Protein Structure Databases --- SwissProt --- Amino Acid Sequence Databases --- Databases, Amino Acid Sequence --- Protein Databases --- Protein Sequence Databases --- SWISS-PROT --- Database, Protein --- Database, Protein Sequence --- Database, Protein Structure --- Databases, Protein Sequence --- Databases, Protein Structure --- Protein Database --- Protein Sequence Database --- Protein Structure Database --- SWISS PROT --- Sequence Database, Protein --- Sequence Databases, Protein --- Structure Database, Protein --- Structure Databases, Protein --- DNA Databanks --- DNA Sequence Databases --- European Molecular Biology Laboratory Nucleotide Sequence Database --- Nucleic Acid Sequence Databases --- RNA Sequence Databases --- DDBJ --- DNA Data Bank of Japan --- DNA Data Banks --- DNA Databases --- Databases, DNA --- Databases, DNA Sequence --- Databases, Nucleic Acid Sequence --- Databases, RNA --- Databases, RNA Sequence --- EMBL Nucleotide Sequence Database --- GenBank --- Nucleic Acid Databases --- RNA Databases --- Bank, DNA Data --- Banks, DNA Data --- DNA Data Bank --- DNA Databank --- DNA Database --- DNA Sequence Database --- Data Bank, DNA --- Data Banks, DNA --- Databank, DNA --- Databanks, DNA --- Database, DNA --- Database, DNA Sequence --- Database, Nucleic Acid --- Database, RNA --- Database, RNA Sequence --- Nucleic Acid Database --- RNA Database --- RNA Sequence Database --- Sequence Database, DNA --- Sequence Database, RNA --- Sequence Databases, DNA --- Sequence Databases, RNA --- Genetic Testing --- Gene Library --- DNA Fingerprinting --- DNA Sequences --- DNA Sequence --- Nucleotide Sequence --- RNA Sequence --- Base Sequences --- Nucleotide Sequences --- RNA Sequences --- Sequence, Base --- Sequence, DNA --- Sequence, Nucleotide --- Sequence, RNA --- Sequences, Base --- Sequences, DNA --- Sequences, Nucleotide --- Sequences, RNA --- Genes --- Nucleotides --- Bio-informatics --- Biological informatics --- Biology --- Information science --- Computational biology --- Systems biology --- Data processing

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When DNA profiling was first introduced into the American legal system in 1987, it was heralded as a technology that would revolutionize law enforcement. As an investigative tool, it has lived up to much of this hype—it is regularly used to track down unknown criminals, put murderers and rapists behind bars, and exonerate the innocent. Yet, this promise took ten turbulent years to be fulfilled. In Genetic Witness, Jay D. Aronson uncovers the dramatic early history of DNA profiling that has been obscured by the technique’s recent success. He demonstrates that robust quality control and quality assurance measures were initially nonexistent, interpretation of test results was based more on assumption than empirical evidence, and the technique was susceptible to error at every stage. Most of these issues came to light only through defense challenges to what prosecutors claimed to be an infallible technology. Although this process was fraught with controversy, inefficiency, and personal antagonism, the quality of DNA evidence improved dramatically as a result. Aronson argues, however, that the dream of a perfect identification technology remains unrealized.

DNA Fingerprinting --- Forensic Medicine --- Forensic genetics --- DNA fingerprinting --- Forensic biology --- Genetics --- Medical jurisprudence --- DNA fingerprints --- DNA identification --- DNA profiles --- DNA profiling --- Genetic fingerprinting --- Genetic fingerprints --- Identification --- DNA Fingerprints --- DNA Profiling --- DNA Typing --- Genetic Fingerprinting --- DNA Fingerprint --- DNA Fingerprintings --- DNA Profilings --- DNA Typings --- Fingerprint, DNA --- Fingerprinting, DNA --- Fingerprinting, Genetic --- Fingerprintings, DNA --- Fingerprintings, Genetic --- Fingerprints, DNA --- Genetic Fingerprintings --- Profiling, DNA --- Typing, DNA --- Typings, DNA --- Paternity --- Polymorphism, Restriction Fragment Length --- Minisatellite Repeats --- Random Amplified Polymorphic DNA Technique --- Databases, Nucleic Acid --- Genetic Privacy --- Genotyping Techniques --- Medicine, Forensic --- Medicine, Legal --- Legal Medicine --- Jurisprudence --- Law Enforcement --- Biometric Identification --- DNA Contamination --- legislation & jurisprudence --- history --- History. --- Technique

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Genetics --- Genetics, Medical --- Genetic Predisposition to Disease --- Genetic Screening --- Genome --- Medical genetics --- Genomics --- Génétique médicale --- Génomique --- Periodicals. --- Périodiques --- Genomes --- Human genome --- Genetics, Medical. --- Genome. --- Genetic Testing. --- Genetic Predisposition to Disease. --- Genomes. --- Human genome. --- Medical genetics. --- Chemistry --- Health Sciences --- Life Sciences --- Biochemistry --- Pathology --- Predisposition, Genetic --- Susceptibility, Genetic --- Genetic Predisposition --- Genetic Susceptibility --- Genetic Predispositions --- Genetic Susceptibilities --- Predispositions, Genetic --- Susceptibilities, Genetic --- Disease Susceptibility --- Predictive Genetic Testing --- Predictive Testing, Genetic --- Testing, Genetic Predisposition --- Genetic Predisposition Testing --- Genetic Predictive Testing --- Genetic Screenings --- Genetic Testing, Predictive --- Predisposition Testing, Genetic --- Screening, Genetic --- Screenings, Genetic --- Testing, Genetic --- Testing, Genetic Predictive --- Testing, Predictive Genetic --- Human Genetics --- Medical Genetics --- Genetics, Human --- genetics --- diagnosis --- Genetic Testing --- Anticipation, Genetic --- Genetic Association Studies --- Gene-Environment Interaction --- Prenatal Diagnosis --- Preimplantation Diagnosis --- Cytogenetic Analysis --- Molecular Diagnostic Techniques --- Databases, Genetic --- Databases, Nucleic Acid --- Genetic Privacy --- Genes --- Proteome --- Anthropology, Physical --- Chromosome Disorders --- Sex Chromosome Disorders --- Genetic Diseases, Inborn --- Molecular Medicine --- Human chromosomes --- Haploidy --- Clinical genetics --- Diseases --- Heredity of disease --- Human genetics --- Medical sciences --- Genetic disorders --- Genetic aspects

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ADN-empreintes génétiques --- DNA fingerprinting --- DNA fingerprints --- DNA identification --- DNA profiles --- DNA profiling --- DNA-vingerafdrukken --- Empreintes ADN --- Empreintes génétiques --- Genetic fingerprinting --- Genetic fingerprints --- Identification génétique --- DNA Fingerprinting. --- Forensic Medicine --- Jurisprudence. --- Forensic genetics --- Identification --- Constitutional Law --- Court Decision --- Law --- Legal Aspects --- Legal Obligations --- Legal Status --- State Interest --- Litigation --- Medical Jurisprudence --- Aspect, Legal --- Aspects, Legal --- Constitutional Laws --- Court Decisions --- Decision, Court --- Decisions, Court --- Interest, State --- Interests, State --- Jurisprudence, Medical --- Law, Constitutional --- Laws --- Laws, Constitutional --- Legal Aspect --- Legal Obligation --- Litigations --- Obligation, Legal --- Obligations, Legal --- State Interests --- Status, Legal --- Defamation --- Lawyers --- DNA Fingerprints --- DNA Profiling --- DNA Typing --- Genetic Fingerprinting --- DNA Fingerprint --- DNA Fingerprintings --- DNA Profilings --- DNA Typings --- Fingerprint, DNA --- Fingerprinting, DNA --- Fingerprinting, Genetic --- Fingerprintings, DNA --- Fingerprintings, Genetic --- Fingerprints, DNA --- Genetic Fingerprintings --- Profiling, DNA --- Typing, DNA --- Typings, DNA --- Paternity --- Polymorphism, Restriction Fragment Length --- Minisatellite Repeats --- Random Amplified Polymorphic DNA Technique --- Databases, Nucleic Acid --- Genetic Privacy --- Genotyping Techniques --- methods. --- Technique --- Australia. --- Canton and Enderbury Islands --- Christmas Island --- Christmas Island (Australia) --- DNA Fingerprinting --- Jurisprudence --- methods --- DNA fingerprints.